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Sales of antihistamines and boxes of tissues go up in winter but especially during the holidays. Here are some of the causes of the spike in allergies: Food – during winter holidays people eat out, with lots of seasonal and unusual foods, and parties where you may not know the ingredients of the foods you are consuming, ending with some unpleasant allergic reaction. Alcohol may affect judgment, and you may forget to check the ingredients to which you are allergic.